🧬 Proteindle

Guess the human protein. Every column is a clue.

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Protein Lengthaa Conservedback to Localization Function Pathway Chr Diseaselinked

Colour key

Conserved back to is the deepest branch of the tree of life where this protein still has a recognisable ortholog, from Universal (bacteria, archaea and eukaryotes alike) up to Mammalia. An arrow pointing down means the answer is older than your guess.

Amber means different things per column: one rung away on the conservation ladder, within 10% on length, an overlapping localization or pathway, or a different function in the same family — guessing a kinase when the answer is a protease gets you amber, because both are enzymes.